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Human papilloma virus infection (HPV) is a very common STI, and multiple HPV types are associated with squamous cell cancers of the cervix, anal canal, and head and neck, as well as condyloma acuminata (anogenital warts). Not surprisingly, a number of cases of neovaginal condyloma acuminata have been reported. Because the preferred technique for neovagina creation is PSI, and penile and scrotal skin are most likely to be affected by HPV, the inversion of the penile skin risks transferring